Total Harmony9 Perimenopause & menopause supplement

Daily support through perimenopause. Every dose on the label.

Nine active ingredients in two daily capsules, formulated in the UK by Katie Watson, who takes it every morning. So does her mum. Every dose is printed on the bottle, so you can see exactly what you are taking.

  • Help with tiredness. Magnesium and vitamin B12 contribute to the reduction of tiredness and fatigue.
  • Support for your mind. Vitamin B5 contributes to normal mental performance and zinc to normal cognitive function.
  • Support for hormonal activity. Vitamin B6 contributes to the regulation of hormonal activity.
  • And the longevity actives most menopause formulas leave out. 300mg NMN, the precursor your cells use to make NAD+, plus 100mg trans-resveratrol. Both have been studied in postmenopausal women. See the research.

60 capsules · 30-day supply · Two capsules daily

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1 bottle · £24.99 today. Then £29.99 every 30 days until cancelled.

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30-day Fair-Try promise: 50% refund on your opened first bottle, 100% on unopened bottles. Read the terms.

Katie Watson, co-founder of Prime Ageing, holding Total Harmony 9 in her kitchen
Meet Katie Watson, co-founder of Prime Ageing.
Her own perimenopause shaped this formula. Two kids, a business to run, and a household that relies on her to remember everyone else’s lives.

Rated 4.9 out of 5 by UK women

Make room for yourself, too

You are not imagining it, and you are not failing at it.

  • The 2pm wallYour brain quietly clocks off without telling you.
  • The dropped wordMid-sentence, in a meeting, in front of people.
  • The 3am ceilingWide awake, too hot, then shattered by seven.
  • The short fuseReacting to things that would not have touched you two years ago.
  • The lost phoneHeld in your hand while you ask the room where it is.
  • The shrug“It is just your age.” As if that settles it.

Perimenopause can start in your late thirties and run for a decade. Most women are offered two options: HRT, or ride it out. Plenty of us are on HRT and still do not feel like ourselves. That gap is where Total Harmony 9 was built.

So here is what went in the bottle for it.

  • For your mind and nervous system

    Magnesium, vitamin B6 and vitamin B12 contribute to normal psychological function and to the normal functioning of the nervous system.

  • For your bones and muscles

    Vitamin D3 and magnesium contribute to the maintenance of normal bones, and vitamin D3 to the maintenance of normal muscle function.

  • For your skin, hair and nails

    Zinc contributes to the maintenance of normal hair, skin and nails, and to the protection of cells from oxidative stress.

Katie Watson at home in her kitchen
Katie Watson · Co-founder of Prime Ageing. Mum of two.
A note from Katie, our co-founder

I kept walking into the kitchen and forgetting why.

Work emails. PE kits. Dinner. A coffee I had made an hour ago and still had not touched. I was keeping track of everyone else’s day while losing the thread of my own.

For a long time I put it down to being busy. Or stressed. Two kids, a business to run, a household that relies on me to remember everyone else’s lives, and I could not remember my own. It turns out it is not a personality flaw.

Watching my mum go through it had been the same story, only louder. The hot flushes at the dinner table. The brain fog she kept apologising for. The shrug, and “it is just my age”, as if every woman before her had been quietly expected to put up with it.

So I went looking for something that understood the biology of what was actually happening, not another bottle with “menopause” printed on the front. Most of what I found was the same B-vitamin formula from twenty years ago, or a fashionable ingredient sprinkled in at a token dose.

So we built Total Harmony 9 instead. Nine actives, every one of them named and dosed on the label, so you can go and check the research yourself rather than take my word for it.

I wanted something that fitted into a real morning. Two capsules. One bottle. Simple enough to sit next to the kettle and survive the school run.

Total Harmony 9 is part of my own morning routine. I take it. So does my mum.

Katie Katie Watson · Co-founder, Prime Ageing

If any of that sounds like your mornings too.

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The full formula

Nine actives. Every dose, and why we chose it.

Two capsules a day. Here is every milligram of what is in them, which form we used, and what that form does differently. Most labels will not tell you the second part.

All amounts are per two-capsule daily serving.

  • Vitamin B6

    P-5-P form
    Support for normal hormonal activity

    Vitamin B6 contributes to the regulation of hormonal activity, normal psychological function, and the reduction of tiredness and fatigue.

    Why P-5-P: it is the form your body already recognises. Cheaper supplements use pyridoxine hydrochloride, which has to be converted first.

    10mg 714% NRV
  • Pantothenic acid

    Vitamin B5
    Support for normal mental performance

    Pantothenic acid contributes to normal mental performance, the reduction of tiredness and fatigue, and the normal synthesis and metabolism of steroid hormones, vitamin D and some neurotransmitters.

    Why 50mg: not the 6mg token dose you will find on most menopause labels.

    50mg 833% NRV
  • Vitamin B12

    Methylcobalamin
    Help with tiredness and fatigue

    Vitamin B12 contributes to the reduction of tiredness and fatigue, normal energy-yielding metabolism, normal functioning of the nervous system, and normal psychological function.

    Why methylcobalamin: the active form, rather than the cyanocobalamin used in most cheaper supplements.

    100µg 4000% NRV
  • Magnesium

    From magnesium bisglycinate
    Support for your nervous system and bones

    Magnesium contributes to normal functioning of the nervous system, normal psychological function, the reduction of tiredness and fatigue, and the maintenance of normal bones.

    Why bisglycinate: it is chelated, and gentler on the stomach than the magnesium oxide used in most supermarket supplements.

    63.5mg 17% NRV
  • Vitamin D3

    2000 IU · vegan D3 from lichen
    Support for bones, muscles and immunity

    Vitamin D contributes to the maintenance of normal bones, normal muscle function, and the normal function of the immune system.

    Why 2000 IU: four times the UK reference intake, because from October onwards most of us in Britain are short of it. From lichen, not lanolin.

    50µg 1000% NRV
  • Zinc

    From zinc picolinate
    Support for cognitive function, skin, hair and nails

    Zinc contributes to normal cognitive function, the protection of cells from oxidative stress, and the maintenance of normal bones, hair, nails and skin.

    Why picolinate: a chelated form, chosen over the zinc oxide that turns up in cheaper multivitamins.

    15mg 150% NRV
  • NMN

    Nicotinamide mononucleotide
    The precursor your body uses to make NAD+

    300mg per daily serving, ultra-pure. This is the ingredient that separates Total Harmony 9 from a menopause multivitamin, and the one almost no other UK formula includes at all.

    Why we included it: the first controlled human trial of NMN was run in postmenopausal women. The research is further down this page.

    300mg No NRV established
  • Trans-resveratrol

    Polyphenol
    A polyphenol studied in postmenopausal women

    100mg of resveratrol in its trans form, the form used in the research, per daily serving.

    Why trans: resveratrol comes in two forms and only the trans form is the one studied. Plenty of labels just say “resveratrol”.

    100mg No NRV established
  • Red clover extract

    Standardised to 8% isoflavones
    A measured dose, not a dusting

    200mg of extract, standardised to provide 16mg of isoflavones per daily serving.

    Why standardised: it means every capsule delivers the same 16mg. An unstandardised extract varies batch to batch, and most labels never state the isoflavone figure at all.

    200mg 16mg isoflavones

NRV = Nutrient Reference Value.

Your daily routine starts with two capsules.

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Why this is not a multivitamin

Two things change in perimenopause. Your hormones only explain one.

Oestrogen is the half everybody talks about. The other half is NAD+, the coenzyme your cells use to turn food into energy. Research measuring it in human tissue has found that NAD+ levels fall as we age.

Almost every menopause formula on a UK shelf addresses the first and ignores the second. Prime Ageing is a longevity company before it is a menopause company, which is why Total Harmony 9 was built to cover both.

  • 300mg NMN

    Your body uses nicotinamide mononucleotide to make NAD+.

    When the first controlled human trial of NMN was run, it was run in postmenopausal women. Twenty-five of them, 250mg a day for ten weeks, published in Science in 2021.

    The detail

    Randomised, placebo-controlled, double-blind. The participants were postmenopausal women with prediabetes who were overweight or obese. The trial measured insulin sensitivity in muscle, not menopause symptoms, and 25 people is a small study. Yoshino et al., Science 2021. Read it yourself.

  • 100mg Trans-resveratrol

    A polyphenol that keeps being studied in this exact group, and rarely in any other.

    129 postmenopausal women aged 45 to 85 took it daily for twelve months. Overall cognitive performance improved against placebo.

    The detail

    Randomised, placebo-controlled. The trial used 150mg a day, split into two doses; Total Harmony 9 contains 100mg alongside eight other actives. A separate paper from the same research programme reported slowed bone loss. Thaung Zaw et al., Nutrients 2020. Read it yourself.

Plus six vitamins and minerals, each with an approved benefit.

Help with tiredness
Magnesium and vitamin B12 Contribute to the reduction of tiredness and fatigue, and to normal energy-yielding metabolism.
Support for hormonal activity
Vitamin B6 Contributes to the regulation of hormonal activity. We use the active P-5-P form rather than the cheaper pyridoxine hydrochloride.
Protection from oxidative stress
Zinc Contributes to the protection of cells from oxidative stress, and to normal cognitive function. From zinc picolinate.
See all nine ingredients and their daily doses
How it compares

Five things worth checking on any bottle.

We checked the 10 best-selling perimenopause supplements on Amazon. 5 of them failed at least three of these. Here is where Total Harmony 9 lands on each.

What to check Total Harmony 9 Typical perimenopause formula
Is every dose printed on the label? All nine, in milligrams Often a “blend” total only
Does it contain NMN? 300mg, ultra-pure Almost never included
Is the isoflavone content stated? 16mg, from 200mg extract Frequently unstated
How many capsules a day? Two, with breakfast Anywhere from two to six
How hard is it to cancel? One click in your account Often email or phone only

Right-hand column based on our review of the 10 best-selling perimenopause supplements on Amazon UK, August 2026. It describes formats common across the category and is not a statement about any named product.

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30-day supply · Buy once or subscribe · Free UK delivery

How it works in practice

Make it part of breakfast. And give it a fair month.

One small addition to a routine you already have, and a straightforward way out if it is not for you.

  1. 01 · Take

    Two capsules, with breakfast

    Your whole daily serving, taken with your first meal. One bottle is 30 daily servings. Put it next to the kettle, because the supplement you remember to take beats the better one you take four mornings out of seven.

  2. 02 · Give it a month

    Long enough to be a fair test

    Nutrient levels build over weeks, not days. Anyone promising you a transformation by Friday is selling you something else. A month is what we would ask for before you make up your mind, which is exactly why the guarantee runs for 30 days and not seven.

  3. 03 · Or change your mind

    No arguing, no forms

    If it has not earned its place next to the kettle, email us. One message to a person who will answer it.

    The terms, in full: within 30 days, 50% back on your opened first bottle and 100% on anything unopened.

A month is about 60 capsules and roughly 83p a day. That is what it costs to find out whether it works for you, and you are not locked into anything if it does not.

From our customers

Real voices. Real harmony.

Every review below is from a verified order.

4.9
★★★★★
5 ★
92%
4 ★
6%
3 ★
1%
2 ★
<1%
1 ★
0%
★★★★★ Verified

Waking up as ‘me’ again.

I finally feel like myself again. After months of that heavy 2pm slump where I felt like a zombie, Total Harmony 9 has actually brought back my spark. It’s not a caffeine buzz, it just feels like my batteries have been replaced. I’m finishing the day with energy left for my family.

JS
Jane S.
Surrey·Perimenopause·4 months in
★★★★★ Verified

The mental haze has finally lifted.

I found brain fog the hardest part of this journey. I’d walk into a room and forget why I was there. Within two weeks of starting, the haze started to lift. I feel sharp, focused, and capable again at work. It’s a massive weight off my shoulders.

SW
Sarah W.
Edinburgh·Menopause·3 months in
★★★★★ Verified

Finally, a peaceful night’s sleep.

I was dreading the nights. The flushes were so disruptive, but the Red Clover and B6 combo have steadied my internal thermostat. I’m sleeping through again and I don’t feel like I’m constantly overheating. A total game-changer.

LG
Linda G.
Cotswolds·Menopause·6 months in
★★★★★ Verified

Quietening the hormonal chaos.

The mood swings were making me feel like a passenger in my own body. I felt so reactive and overwhelmed. Total Harmony has helped me find a sense of calm and balance I haven’t felt in years. I feel steady, grounded, and much more like myself.

RT
Rachel T.
London·Perimenopause·2 months in
★★★★★ Verified

Genuinely restorative rest.

I haven’t slept this well in ages. The Magnesium in this formula is so much gentler on my stomach than other brands I’ve tried, and it really helps me switch off at night. I wake up feeling genuinely restored, not just ‘rested’.

KB
Karen B.
Manchester·Post-menopause·5 months in
★★★★★ Verified

My entire ritual in one bottle.

I used to take five different supplements, but having NMN, Red Clover, and all the essential vitamins in two pills a day is so much easier. It’s become my daily ritual for keeping the chaos at bay, and my husband’s noticed the difference too.

MJ
Michelle J.
Yorkshire·Post-menopause·8 months in
A bottle of Total Harmony 9 on a kitchen worktop

One bottle. A simpler daily routine.

  • Nine named actives. Every daily dose printed on the label, no proprietary blend.
  • Two capsules daily. Thirty daily servings per bottle.
  • Your choice. Buy once, or have it arrive so you never run out.
  • Cancel in one click from your account, any time, including before your second delivery.
  • Free UK delivery on every order.
Total Harmony 9

Choose your daily support.

Start with one bottle, or save more per bottle with a 90-day supply. Your discount is applied at checkout. No code to remember.

Free UK delivery on every order. Two capsules daily · 30 days per bottle.

Choose your purchase option

1 bottle · £24.99 today. Then £29.99 every 30 days until cancelled.

About 83p a day for your first 30 days, then £1.00 a day.

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Your 30-day Fair-Try promise

50% refund on your opened first bottle, 100% on unopened bottles. One email, no form to fill in. Read the full terms.

View the full ingredients and daily doses Total Harmony 9 nutrition panel showing every ingredient and amount per two-capsule daily serving Open the label at full size (new tab)
Common questions

Your questions, honestly answered.

The things UK women in midlife actually ask us, including the awkward ones.

Before you order

No. Choose one bottle with nothing recurring, or a subscription if you would rather it arrived on its own. Both are on the same buying panel and the one-off option is not hidden behind anything.

Skip, pause, reschedule or cancel with one click from your account, any time, including before your second delivery ever ships.

No phone call, no email chain, no minimum term and nobody trying to talk you out of it. It takes about ten seconds.

Our 30-day fair-try promise: 50% back on an opened first bottle, 100% back on anything unopened. Email us and we will handle it, there is no form to fill in.

We call it fair-try rather than risk-free, because a partial refund is not risk-free and we are not going to pretend otherwise on the way to taking your money.

UK delivery is free on every order, sent on Royal Mail Tracked 48 and usually arriving two to three working days after dispatch.

Orders placed before 3pm on a working day are normally dispatched the same day. Tracking lands by email as soon as it is on its way.

Thirty days. Sixty capsules, two a day with your first meal. That is the entire routine.

Taking it safely

Many of our customers take it alongside HRT. Total Harmony 9 is a food supplement, not a medicine and not a replacement for HRT.

Because the formula contains red clover isoflavones, which are plant compounds with a weak oestrogen-like structure, please ask your pharmacist or prescriber to check the full ingredient list against your treatment before you start. Take them this page. It costs five minutes and it is worth doing properly.

Please do not take it if you are pregnant or breastfeeding, or if you have a current or previous oestrogen-sensitive cancer, a history of blood clots, or liver disease. That is because of the red clover isoflavones.

If you are on prescription medication, particularly anticoagulants, or under the care of a specialist, speak to them first. If you are having treatment for cancer, speak to your oncology team about any supplement before taking it, this one included.

We would rather lose the sale than have you order something that is wrong for you.

No. The tolerable upper intake level for adults is 4000 IU a day, so 2000 IU sits well within it, and the NHS suggests most UK adults consider a daily vitamin D supplement in autumn and winter.

If you already take a separate vitamin D supplement, check your combined daily total rather than taking both without looking.

The formula

Nicotinamide mononucleotide. It is a precursor your body uses to make NAD+, a coenzyme involved in energy production inside every cell. NAD+ levels fall as we get older.

Total Harmony 9 contains 300mg of ultra-pure NMN in every daily serving. That is a meaningful dose rather than a token sprinkle, and it is the ingredient that separates this from a standard menopause multivitamin. The exact amount is printed on the label, so you can look up the research yourself rather than take our word for it.

P-5-P is the active form of vitamin B6, the one the body already uses. Cheaper supplements use pyridoxine hydrochloride, which has to be converted first.

It costs us more per capsule. It is one of the few places on a label where the difference is visible if you know to look.

Yes, fully plant-based. Vegetable cellulose capsule, D3 from lichen rather than lanolin, no gelatin, dairy, talc, magnesium stearate or artificial colouring.

What is on the label is what is in the bottle. Nothing else.

Manufactured in the UK in a GMP-certified facility, with third-party testing on every batch.

Email us the lot number on your bottle and we will send you the certificate of analysis for that batch.

Perimenopause commonly begins in the early forties and can start in the late thirties. It often runs for several years before periods stop, and it is frequently missed at that stage because cycles can still be regular.

Total Harmony 9 is a food supplement suitable for adult women through perimenopause, menopause and afterwards.

Anything we have not covered? A person answers every email, usually within a day.

hello@primeageing.co.uk

One decision left

Nine actives, every dose printed, from 78p a day.

Two capsules with breakfast. Free UK delivery, and cancel in one click whenever you like. If it has not earned its place in 30 days, tell us and we will put it right.

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